BRCA2 promotes DNA‐RNA hybrid resolution by DDX5 helicase at DNA
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Descrição
BRCA2 promotes DNA-RNA hybrid resolution at DNA breaks to facilitate homologous recombination
R-Loops and Its Chro-Mates
Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence
DICER ribonuclease removes harmful R-loops - ScienceDirect
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Full article: A new interaction between BRCA2 and DDX5 promotes the repair of DNA breaks at transcribed chromatin
DNA-RNA hybrids at DSBs interfere with repair by homologous recombination
DDX5 resolves R-loops at DNA double-strand breaks to promote DNA repair and avoid chromosomal deletions. - Abstract - Europe PMC
Full article: Creation and resolution of non-B-DNA structural impediments during replication
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