GPC2-CAR T cells tuned for low antigen density mediate potent
Por um escritor misterioso
Descrição
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
Cancers, Free Full-Text
Reprogramming T cell differentiation and exhaustion in CAR-T cell therapy, Journal of Hematology & Oncology
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors
JCM, Free Full-Text
JCM, Free Full-Text
GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma
Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
BiCisCAR T cells targeting both GPC2 and CD276 show potent NB
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors. - Abstract - Europe PMC
Strategies to enhance CAR-T persistence, Biomarker Research
Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma - ScienceDirect
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